We believe this is among the most comprehensive reviews of the 343-year journey of biofilm observation and research, with particular respect to the foundational papers and scientists who shaped the field.
From Antonie van Leeuwenhoek’s observations of dental plaque in 1683 to today’s understanding of biofilms in acute and chronic wounds, this history shows how far the science has come and how much it continues to influence modern wound care.
For wound care professionals entering this fascinating field, this is a must-read, a connection between scientific history, clinical practice, and the deeply human mission of improving healing and quality of life.
Reference
Percival SL, Swann MJ, Daly K, Mayer D, Moodley P, Chen R. An update on biofilms in acute and chronic wounds: Incidence, clinical evidence, diagnosis, prevention, and treatment. J Intern Med. 2026; 300: 420–439.
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