The ADA has spoken—and the evidence is Grade A.
The American Diabetes Association (ADA) continues its highest-level, evidence-based recommendation for Topical Oxygen Therapy (TOT) in the management of chronic Diabetic Foot Ulcers (DFUs).
This isn’t opinion.
This is Grade 🅰️ evidence—reserved only for therapies supported by large, well-designed randomized controlled trials.
đź“– ADA Standards of Care (2025) state clearly:
“Adjunctive use of topical oxygen therapy is recommended for non-healing diabetic foot ulcers.” (Evidence Grade: A)
Indicative Ref
News and views. Int Wound J. 2023 Feb 14;20(3):617–20. doi: 10.1111/iwj.14115. PMCID: PMC9927900.
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